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1

A harmonization effort for acceptable daily exposure application to pharmaceutical manufacturing – Operational considerations

Hayes, Eileen P., Jolly, Robert A., Faria, Ellen, Barle, Ester Lovsin, Bercu, Joel, Molnar, Lance, Naumann, Bruce, Olson, Michael, Pecquet, Alison, Sandhu, Reena, Shipp, Bryan K., Sussman, Robert, Wei

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 900 KB

english, 2016

2

Spirituality in Addictions Treatment: Wisdom to Know…What It Is

Sussman, Steve, Milam, Joel, Arpawong, Thalida E., Tsai, Jennifer, Black, David S., Wills, Thomas A.

Journal:

Substance Use & Misuse

Year:

2013

Language:

english

File:

PDF, 395 KB

english, 2013

3

Function and structure of inherently disordered proteins

A Keith Dunker, Israel Silman, Vladimir N Uversky, Joel L Sussman

Journal:

Current Opinion in Structural Biology

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

4

JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia

Hanson, Robert M., Prilusky, Jaime, Renjian, Zhou, Nakane, Takanori, Sussman, Joel L.

Journal:

Israel Journal of Chemistry

Year:

2013

Language:

english

File:

PDF, 10.36 MB

english, 2013

5

Novel multitarget-directed ligands targeting acetylcholinesterase and σ1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase

Lalut, Julien, Santoni, Gianluca, Karila, Delphine, Lecoutey, Cédric, Davis, Audrey, Nachon, Florian, Silman, Israel, Sussman, Joel, Weik, Martin, Maurice, Tangui, Dallemagne, Patrick, Rochais, Christ

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

6

The design and evaluation of a high-performance earth science database

Carter T. Shock, Chialin Chang, Bongki Moon, Anurag Acharya, Larry Davis, Joel Saltz, Alan Sussman

Journal:

Parallel Computing

Year:

1998

Language:

english

File:

PDF, 1.85 MB

english, 1998

7

Comparison of the crystal structures of genetically engineered human manganese superoxide dismutase and manganese superoxide dismutase from thermus thermophilus: Differences in dimer–dimer interaction

Ulrike G. Wagner, Felix Frolow, Joel L. Sussman, Katherine A. Pattridge, Martha L. Ludwig, William C. Stallings, Moshe M. Werber, Christian Oefner

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 5.22 MB

english, 1993

8

Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

Yoseph Shaaltiel, Daniel Bartfeld, Sharon Hashmueli, Gideon Baum, Einat Brill-Almon, Gad Galili, Orly Dym, Swetlana A. Boldin-Adamsky, Israel Silman, Joel L. Sussman, Anthony H. Futerman, David Avieze

Journal:

Plant Biotechnology Journal

Year:

2007

Language:

english

File:

PDF, 325 KB

english, 2007

9

Insights into protein adaptation to a saturated salt environment from the crystal structure of a halophilic 2Fe-2S ferredoxin

Frolow, Felix, Harel1, Michal, Sussman, Joel L., Mevarech, Moshe, Shoham, Menachem

Journal:

Natural Structural Biology

Year:

1996

File:

PDF, 728 KB

1996

10

Acetylcholinesterase: From 3D structure to function

Hay Dvir, Israel Silman, Michal Harel, Terrone L. Rosenberry, Joel L. Sussman

Journal:

Chemico-Biological Interactions

Year:

2010

Language:

english

File:

PDF, 2.34 MB

english, 2010

11

eMovie: a storyboard-based tool for making molecular movies

Eran Hodis, Gideon Schreiber, Kristian Rother, Joel L. Sussman

Journal:

Trends in Biochemical Sciences

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

12

The α / β hydrolase fold

Ollis, David L., Cheah, Eong, Cygler, Miroslaw, Dijkstra, Bauke, Frolow, Felix, Franken, Sybille M., Harel, Michal, Remington, S. Jamse, Silman, Israel, Schrag, Joseph, Sussman, Joel L., Verschueren,

Journal:

Protein Engineering Design and Selection

Year:

1992

Language:

english

File:

PDF, 6.63 MB

english, 1992

13

Refined crystal structure of dogfish M4 apo-lactate dehydrogenase

Celerino Abad-Zapatero, James P. Griffith, Joel L. Sussman, Michael G. Rossmann

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 1.96 MB

english, 1987

14

3D structure of mammalian paraoxonase at 2.2 Å resolution

Joel Sussman, Amir Aharoni, Michal Harel, Leonid Gaidukov, Boris Brumshtein, Olga Khersonsky, Shai Yagur, Lilly Toker, Israel Silman, Dan Tawfik

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 70 KB

english, 2006

15

The X-ray Structure of a Transition State Analog Complex Reveals the Molecular Origins of the Catalytic Power and Substrate Specificity of Acetylcholinesterase

Harel, Michal, Quinn, Daniel M., Nair, Haridasan K., Silman, Israel, Sussman, Joel L.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 235 KB

english, 1996

16

Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: A proof-of-concept study

Worek, Franz, Seeger, Thomas, Reiter, Georg, Goldsmith, Moshe, Ashani, Yacov, Leader, Haim, Sussman, Joel L., Aggarwal, Nidhi, Thiermann, Horst, Tawfik, Dan S.

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 1.93 MB

english, 2014

17

Post-traumatic growth, stressful life events, and relationships with substance use behaviors among alternative high school students: A prospective study

Arpawong, Thalida E., Sussman, Steve, Milam, Joel E., Unger, Jennifer B., Land, Helen, Sun, Ping, Rohrbach, Louise A.

Journal:

Psychology and Health

Year:

2015

Language:

english

File:

PDF, 184 KB

english, 2015

18

Nicotine patch and paroxetine for smoking cessation.

Killen, Joel D., Fortmann, Stephen P., Schatzberg, Alan F., Hayward, Chris, Sussman, Lisa, Rothman, Micol, Strausberg, Laura, Varady, Ann

Journal:

Journal of Consulting and Clinical Psychology

Year:

2000

Language:

english

File:

PDF, 880 KB

english, 2000

19

Structural studies on vertebrate and invertebrate acetylcholinesterases and their complexes with functional ligands

Harry M. Greenblatt, Israel Silman, Joel L. Sussman

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 379 KB

english, 2000

20

Analysis of dihedral angles distribution: The doublets distribution determines polypeptides conformations

Ron Unger, David Harel, Scot Wherland, Joel L. Sussman

Journal:

Year:

1990

Language:

english

File:

PDF, 594 KB

english, 1990

21

Letter to the Editor

Edward N. Baker, Tom L. Blundell, Mamannamana Vijayan, Eleanor Dodson, Guy Dodson, Gary L. Gilliland, Joel L. Sussman

Journal:

Year:

1996

Language:

english

File:

PDF, 104 KB

english, 1996

22

Proteopedia: A collaborative, virtual 3D web-resource for protein and biomolecule structure and function

Eran Hodis, Jaime Prilusky, Joel L. Sussman

Journal:

Biochemistry and Molecular Biology Education

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

23

6-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-Glucosidase

Boris Brumshtein, Matilde Aguilar-Moncayo, M. Isabel García-Moreno, Carmen Ortiz Mellet, José M. García Fernández, Israel Silman, Yoseph Shaaltiel, David Aviezer, Joel L. Sussman, Anthony H. Futerman

Journal:

Year:

2009

Language:

english

File:

PDF, 458 KB

english, 2009

24

Design and Synthesis of Peptides That Bind α-Bungarotoxin with High Affinity and Mimic the Three-Dimensional Structure of the Binding Site of Acetylcholine Receptor

Ephraim Katchalski-Katzir, Roni Kasher, Moshe Balass, Tali Scherf, Michal Harel, Mati Fridkin, Joel L. Sussman, Sara Fuchs

Journal:

Year:

2003

File:

PDF, 55 KB

2003

25

A simulation and data analysis system for large-scale, data-driven oil reservoir simulation studies

Tahsin Kurc, Umit Catalyurek, Xi Zhang, Joel Saltz, Ryan Martino, Mary Wheeler, Małgorzata Peszyńska, Alan Sussman, Christian Hansen, Mrinal Sen, Roustam Seifoullaev, Paul Stoffa, Carlos Torres-Verdin

Journal:

Concurrency and Computation: Practice and Experience

Year:

2005

Language:

english

File:

PDF, 1.99 MB

english, 2005

26

A paradigm for single nucleotide polymorphism analysis: The case of the acetylcholinesterase gene

Yehudit Hasin, Nili Avidan, Dani Bercovich, Amos Korczyn, Israel Silman, Jacques S. Beckmann, Joel L. Sussman

Journal:

Year:

2004

Language:

english

File:

PDF, 514 KB

english, 2004

27

Study of istradefylline in patients with Parkinson's disease on levodopa with motor fluctuations

Robert A. Hauser, Lisa M. Shulman, Joel M. Trugman, John W. Roberts, Akihisa Mori, Rocco Ballerini, Neil M. Sussman

Journal:

Movement Disorders

Year:

2008

Language:

english

File:

PDF, 150 KB

english, 2008

28

Active semantic caching to optimize multidimensional data analysis in parallel and distributed environments

Henrique Andrade, Tahsin Kurc, Alan Sussman, Joel Saltz

Journal:

Parallel Computing

Year:

2007

Language:

english

File:

PDF, 809 KB

english, 2007

29

Interstitial brachytherapy for soft tissue sarcoma: A single institution experience

Michelle L. Mierzwa, Connie M. McCluskey, William L. Barrett, Andrew Lowy, Jeffrey Sussman, Joel Sorger

Journal:

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

30

Noncovalent interaction or chemical bonding between alkaline earth cations and benzene? A quantum chemistry study using MP2 and density-functional theory methods

Xiao Jian Tan, Wei Liang Zhu, Meng Cui, Xiao Min Luo, Jian De Gu, Israel Silman, Joel L Sussman, Hua Liang Jiang, Ru Yun Ji, Kai Xian Chen

Journal:

Chemical Physics Letters

Year:

2001

Language:

english

File:

PDF, 257 KB

english, 2001

31

Optimizing execution of component-based applications using group instances

Michael D. Beynon, Tahsin Kurc, Alan Sussman, Joel Saltz

Journal:

Future Generation Computer Systems

Year:

2002

Language:

english

File:

PDF, 446 KB

english, 2002

32

Distributed processing of very large datasets with DataCutter

Michael D Beynon, Tahsin Kurc, Umit Catalyurek, Chialin Chang, Alan Sussman, Joel Saltz

Journal:

Parallel Computing

Year:

2001

Language:

english

File:

PDF, 436 KB

english, 2001

33

Processing large-scale multi-dimensional data in parallel and distributed environments

Michael Beynon, Chialin Chang, Umit Catalyurek, Tahsin Kurc, Alan Sussman, Henrique Andrade, Renato Ferreira, Joel Saltz

Journal:

Parallel Computing

Year:

2002

Language:

english

File:

PDF, 500 KB

english, 2002

34

Design and synthesis of peptides that bind α-bungarotoxin with high affinity and mimic the three-dimensional structure of the binding-site of acetylcholine receptor

Ephraim Katchalski-Katzir, Roni Kasher, Moshe Balass, Tali Scherf, Michal Harel, Mati Fridkin, Joel L. Sussman, Sara Fuchs

Journal:

Biophysical Chemistry

Year:

2003

Language:

english

File:

PDF, 2.15 MB

english, 2003

35

External and internal electrostatic potentials of cholinesterase models

Clifford E Felder, Simone A Botti, Shneior Lifson, Israel Silman, Joel L Sussman

Journal:

Journal of Molecular Graphics and Modelling

Year:

1997

Language:

english

File:

PDF, 997 KB

english, 1997

36

Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins

Miroslaw Cygler, Joseph D. Schrag, Joel L. Sussman, Michal Harel, Israel Silman, Mary K. Gentry, Bhupendra P. Doctor

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 8.32 MB

english, 1993

37

Structure and dynamics of the active site gorge of acetylcholinesterase: Synergistic use of molecular dynamics simulation and X-ray crystallography

Paul H. Axelsen, Michal Harel, Israel Silman, Joel L. Sussman

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 9.08 MB

english, 1994

38

Soluble monomeric acetylcholinesterase from mouse: Expression, purification, and crystallization in complex with fasciculin

Pascale Marchot, Raimond B.G. Ravelli, Mia L. Raves, Yves Bourne, Daniel C. Vellom, Joan Kanter, Shelley Camp, Joel L. Sussman, Palmer Taylor

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 2.59 MB

english, 1996

39

Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations

Benoît Sanson, Jacques-Philippe Colletier, Yechun Xu, P. Therese Lang, Hualiang Jiang, Israel Silman, Joel L. Sussman, Martin Weik

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 255 KB

english, 2011

40

Context-dependent resistance to proteolysis of intrinsically disordered proteins

Marcin J. Suskiewicz, Joel L. Sussman, Israel Silman, Yosef Shaul

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 322 KB

english, 2011

41

The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded

Tzviya Zeev-Ben-Mordehai, Edwin H. Rydberg, Ariel Solomon, Lilly Toker, Vanessa J. Auld, Israel Silman, Simone Botti, Joel L. Sussman

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2003

Language:

english

File:

PDF, 599 KB

english, 2003

42

Proteomic signatures: Amino acid and oligopeptide compositions differentiate among phyla

Itsik Pe'er, Clifford E. Felder, Orna Man, Israel Silman, Joel L. Sussman, Jacques S. Beckmann

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2004

Language:

english

File:

PDF, 4.87 MB

english, 2004

43

Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome

Peter Tsvetkov, Gad Asher, Aviv Paz, Nina Reuven, Joel L. Sussman, Israel Silman, Yosef Shaul

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 427 KB

english, 2008

44

Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12

Sankar Manicka, Yoav Peleg, Tamar Unger, Shira Albeck, Orly Dym, Harry M. Greenblatt, Gleb Bourenkov, Victor Lamzin, Sankaran Krishnaswamy, Joel L. Sussman

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 771 KB

english, 2008

45

Assessment of disorder predictions in CASP8

Orly Noivirt-Brik, Jaime Prilusky, Joel L. Sussman

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 428 KB

english, 2009

46

Assessment of CASP8 structure predictions for template free targets

Moshe Ben-David, Orly Noivirt-Brik, Aviv Paz, Jaime Prilusky, Joel L. Sussman, Yaakov Levy

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 1.64 MB

english, 2009

47

A 3D building blocks approach to analyzing and predicting structure of proteins

Ron Unger, David Harel, Scot Wherland, Joel L. Sussman

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 1.34 MB

english, 1989

48

The importance of short structural motifs in protein structure analysis

Ron Unger, Joel L. Sussman

Journal:

Journal of Computer-Aided Molecular Design

Year:

1993

Language:

english

File:

PDF, 1001 KB

english, 1993

49

π Turn is a conformational pattern in RNA loops and bends

KIM, SUNG-HOU, SUSSMAN, JOEL L.

Journal:

Year:

1976

File:

PDF, 169 KB

1976

50

Crystal structure of a eukaryotic initiator tRNA

SCHEVITZ, RICHARD W., PODJARNY, ALBERTO D., KRISHNAMACHARI, N., HUGHES, JOHN J., SIGLER, PAUL B., SUSSMAN, JOEL L.

Journal:

Year:

1979

File:

PDF, 618 KB

1979

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